The biological clock is a complex system that regulates the circadian rhythms of the body, including sleep-wake cycles, metabolism, and hormonal regulation. The clock is composed of a set of genes and proteins that interact with each other to generate a rhythmic oscillation of about 24 hours. The clock is entrained by environmental cues, such as light and food, and is influenced by genetic and epigenetic factors.
Influence on Aging and Longevity
Studies have shown that the clock plays a crucial role in aging and longevity. For instance, mice with free-running periods of about 24 hours live longer than mice whose periods deviate significantly from 24 hours. Moreover, interventions that restore proper circadian rhythmicity improve longevity in mice.