The new method, developed by an international team of scientists, involves the plasma activation of hydrogel dressings with a unique mix of different chemical oxidants. This process effectively decontaminates and aids healing in chronic wounds, providing a significant advance in tackling antibiotic resistance pathogens. Chronic wounds pose a significant global health challenge, with more than 540 million people living with diabetes worldwide, of which 30 per cent will develop a foot ulcer during their lifetime.
Decontamination and Healing Enhancement
The plasma activation of the hydrogel dressings generates a combination of different oxidants, including reactive oxygen and nitrogen species. This unique mix effectively decontaminates the wound by targeting and eradicating a broad spectrum of pathogenic microorganisms, including antibiotic-resistant bacteria.
Furthermore, the activated hydrogel dressings promote the healing process by stimulating the body’s natural wound healing mechanisms. The generated oxidants trigger cellular signaling pathways that enhance the migration and proliferation of skin cells, accelerating the closure of the wound.