Zombie neurons refer to neurons that appear to function normally but actually contain errors in their genetic makeup. These errors can lead to impaired brain function, similar to the behavior exhibited by fictional zombies. By studying these neurons, researchers hope to gain a better understanding of how our brains process information and correct errors.
Despite their seemingly negative implications, zombie neurons offer several advantages when it comes to recording applications. They can be edited at varying rates, allowing researchers to analyze different levels of genetic mutation. Additionally, their strong targeting specificity and accurate amplification and readout make them valuable tools for studying memory units and reconstructing lineage information in embryos, brains, and tumors.